Sections
Slide 1: Sections of renal tissues of, (a) control rats receiving distilled water only, (b) rats receiving soya beans oil only, (c) rats receiving 40.0mg NCT/kg bwt, (d) rats receiving 40.0 mg NCT/kg bwt+200 mg Vitamin C/kg bwt, (e) rats receiving 40.0mg NCT/kg bwt+200IU Vitamin E/kg bwt and (f) rats receiving 40.0mg NCT/kg bwt+200IU Vitamin E/kg bwt+200mg Vitamin C/kg bwt. Slides 1a and b show normal kidney tissues showing prominent glomeruli (GL) and renal tubules (RT). The glomeruli are surrounded by clear bowman's space (BS) and a cellular mesangium (MS) consisting of deeply stained basophilic oval to round mesangial cells. The renal tubules are closely packed with empty lumen, lined by cuboidal epithelial cells with regular cellular outline. Also, the intervening interstitium is scanty and contains normal blood vessels. Slide 1c shows atrophic glomeruli and some swollen glomeruli with loss of bowman space. Their mesangial cells are scanty with areas of fibrosis. The renal tubules are closely packed and lined by swollen epithelial cells with some tubules showing detachment of epithelial cells from their basement membrane. Also, the intervening interstitium is scanty and contains congested blood vessels and thick wall arterioles. Slide 1d, e and f show prominent glomeruli and renal tubules. The glomeruli are surrounded by clear bowman's space and a cellular mesangium. The renal tubules are closely packed with empty lumen, lined by cuboidal epithelial cells having regular cellular outline and moderate eosinophilic cytoplasm and prominent nuclei with nucleoli. Also, the intervening interstitium is scanty and contains blood vessels.