Treatment
Total No. of cells analysed per mice
No. of cells with micronuclei
% age of MN
% Reduction
P value
Group 1
Negative Control (Distilled water)
1000
2.35 ± 0.12
Group 2
Positive control (EMS)
1000
7.23 ± 0.89
0.05*
Group 3
Ab- EAE 100 mg/kg bw
1000
2.32 ± 0.08
Group 4
Ab- EAE 400 mg/kg bw
1020
2.30 ± 0.05
Group 5
Ab- EAE 100 mg/kg + EMS
1000
7.09 ± 0.76
98
2
Group 6
Ab-EAE 200 mg/kg + EMS
1000
6.88 ± 0.54
95.1
4.9
0.05*
Group 7
Ab-EAE 300 mg/kg + EMS
1000
6.05 ± 0.45
83.6
16.4
0.05*
Group 8
Ab-EAE 400 mg/kg + EMS
1000
5.74 ± 0.35
79.3
20.7
0.05*
Table 4:
Effects of Ethyl Acetate Extract of
Ajuga bracteos
a on MNPCE frequencies (mean ± SD) in mice, induced with ethyl methane sulfonate (EMS) 117.5 mg/kg bw (1/4th LD50). Ab-EAE = Ethyl Acetate extract of
Ajuga bracteos
a
