Treatments Chromosomal Aberrations Concentration (mg/kgbw) No. of cells Rings Fragments Exchange Breaks Dicentrics Gaps Total Aberrations %age of Aberrations Distilled water 1004 2 6 - 15 - - 23 2.29 EMS 117.5 mg/kg bw 1020 8 35 28 123 - 62 256 25.09 Ab-EAE Alone 100 mg/kg bw 1000 3 4 - 14 - - 21 2.1 Ab-EAE Alone 400 mg/kg bw 1000 2 6 - 12 - - 20 2 Ab-EAE 100 mg/kg bw + EMS 1005 8 32 24 102 3 38 207 20.59 Ab-EAE 200 mg/kg bw + EMS 1000 6 28 20 86 - 26 166 16.5 Ab-EAE 300 mg/kg bw+ EMS 1005 4 24 18 62 1 18 127 12.63 Ab-EAE 400 mg/kg bw + EMS 1015 2 18 14 38 - 12 84 8.27

Table 5:Frequency of Chromosomal aberrations observed after post-treatment with Ethyl Acetate extract of Ajuga bracteosa in EMS treated mouse bone marrow cells. Ab-EAE=Ethyl Acetate extract of Ajuga bracteosa