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Figure 4: Ca2+ imaging of Zn-intoxicated GT1-7 cells. A: Pseudocolor images of [Ca2+]i of GT1-7 cells B: A solution of ZnCl2 (250 μM) was applied onto fura-2-loaded GT1-7 cells without (a) or with preadministration of 100 μM Al3+ (b). Temporal changes of fluorescence intensities corresponding to increases in [Ca2+]i before and after the exposure to Zn2+ were depicted. Arrows indicate the time of exposure. |