Figure 4: Comparison of papillary muscle contractile force (N) in saline, CAV and Tropi+ CAV groups. Contractility force in CAV and Tropi+ CAV groups decreased vs. saline group (CAV group P< 0.001; CAV+ Tropi group p=0.01). Further tropisetron was able to repair the cardiotoxicity- induced by CAV as contractility force in group receiving tropisetron increased in comparison with CAV group (p= 0.038). Data are presented as mean± S.E.M of 6 rats.