Study groups |
Heart rate |
Q-T interval |
Saline |
322.0± 5.9 |
61.2± 3.6 |
CAV |
267.1± 6.4 ** |
93.8± 5.2*** |
CAV+ Tropi |
290.2± 5.7 *# |
77.2± 2.5 *# |
CAV chemotherapy led to bradycardia and Q-T interval prolongation while
tropisetron pretreatment could prevent heart rate and ECG changes in CAV+ Tropi
group. Values are the mean ± S.E.M of 6 rats.
*p< 0.05; **p<0.01; ***p<0.001 compared to saline group.
#p< 0.05 compared to CAV group. |
