Figure 3: Effect of DOX in combination with iron and thiol reagents on the membrane potential of mitochondria. Enhancement of the effect of DOX by iron (A, 100 μM FeCl3 or FeSO4 ) and thiol reagents (B, 50 μM NEM or 200 μM buterol); a comparison of the effect of iron, NEM, and buterol on the rate of DOX-induced decrease in the mitochondrial membrane potential (C). Statistical significance *p < 0.05.