Table 3

	Placebo			Alcohol			Two-way ANOVA P value
Parameters	0% GTP (P)	0.1% GTP (PLG)	0.5% GTP (PHG)	0% GTP (A)	0.1% GTP (ALG)	0.5% GTP (AHG)	Alcohol	GTP	Alcohol GTP
BV/TV (%)	8.41 ± 0.49^x	7.51 ± 0.49^x	8.41 ± 0.46^x	5.98 ± 0.52^y	5.83 ± 0.49^y	5.35 ± 0.46^y	<0.001	0.572	0.356
Tb.N (1/mm³)	2.356 ± 0.141^x	2.087 ± 0.141^x	2.368 ± 0.133^x	1.743 ± 0.151^y	1.509 ± 0.141^y	1.521 ± 0.133^y	<0.001	0.222	0.567
Tb.Th (mm)	0.056 ± 0.001^x	0.055 ± 0.001^x	0.055 ± 0.001^x	0.052 ± 0.001^y	0.054 ± 0.001^y	0.052 ± 0.001^y	0.004	0.524	0.417
Tb.Sp (mm)	0.421 ± 0.041^y	0.468 ± 0.041^y	0.427 ± 0.039^y	0.686 ± 0.045^x	0.660 ± 0.041^x	0.669 ± 0.039^x	<0.001	0.921	0.678
Conn Dens (1/mm)	31.82 ± 3.05^x	25.21 ± 2.85^x	31.49 ± 2.69^x	21.89 ± 3.05^y	21.82 ± 0.30^y	16.95 ± 2.69^y	<0.001	0.508	0.156
SMI	2.55 ± 0.05^y	2.60 ± 0.05^y	2.53 ± 0.04^y	2.76 ± 0.05^x	2.73 ± 0.03^x	2.82 ± 0.04^x	<0.001	0.916	0.240

Alcohol negatively affected all parameters of trabecular bone in the Tibia

Table 3: Trabecular bone parameters of the tibia measured in placebo - and alcohol-treated rats supplemented with green tea polyphenols (GTP) in drinking water are shown. Results are expressed as mean values ± standard error of mean (SEM). All dietary treatment groups were analyzed by two-way analysis of variance (ANOVA) followed by Fisher’s protected least significant difference (Fisher’s LSD) post-hoc test to evaluate the effect of alcohol, GTP dose, or interaction. Within a row with different superscripts (x and y for alcohol effect; a and b for GTP; A, B and C for interaction) are significantly different by two-way ANOVA and Fisher’s LSD test (P<0.05). Max force, maximal force. Abbreviations are: BV/TV, bone volume/total volume; Tb.N, trabecular number; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation; Conn Dens, connectivity density; SMI, structural model index.