| Parameter |
Conventional dosage form |
GRDDS |
| Toxicity |
Higher toxicity risk |
Lower toxicity risk |
| Patient compliance |
Lower level |
Higher level |
| Dose dumping |
Lower risk of dose dumping |
Higher risk of dose dumping if technology fails |
| Adverse effects |
Higher chances |
Chances are reduced due to fewer blood level peaks outside therapeutic range |
| Overall health care cost |
May be higher |
In spite of higher initial cost, overall treatment cost may be less due to improved therapeutic benefit, fewer side effects, reduced time for health care personnel to dispense and administer drugs and monitor patients |
*Gastro retentive drug delivery systems (GRDDS) |
