| Method | 
        Techniques | 
        Equipment | 
       
      
        | Mechanical | 
        crushing 
          shearing 
          grinding 
          pulverizing | 
        mortar and pestle, coffee grinder,hammer, blender, worm drive clamp, cheese grater | 
       
      
        | Chemical | 
        dissolution 
          solvent    extraction | 
        water, beer, wine, spirits, soda,lemon juice, household cleaners | 
       
      
        | Thermal | 
        heating 
          freezing | 
        oven, microwave, freezer, liquid    nitrogen, dry ice | 
       
      
        | Oral | 
        chewing 
          multiple administration | 
        saliva, masticatory force | 
       
      
        | Parenteral | 
        syringeability 
          injectability 
          filtration | 
        needle, syringe, cotton filter,cigarette filter, spoon, heat source | 
       
      
        | Insufflation | 
        crush | 
        straw, bill, pen, spray bottle | 
       
      
        | Inhalation | 
        burn or heat | 
        lighter, stove, candle, aluminum    foil | 
       
      |