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Figure 7: Ultrastructural observations of Vero cells infected with amastigotes of T. cruzi for 72 h. (a) Untreated infected culture. (b, c and d) Infected cells when treated with 1 mM of compound 1 for 24 h showed parasites in different stages of destruction and disruption in the cytoplasm of the host cell. M=Mitochondria, K=kinetoplast, A=amastigote, Star=amastigotes at an advanced stage of destruction. Scale bars: A=2 μm; B,D=1 μm; C=0.5 μm. |