Groups SGOT (U/ L) SGPT (U/ L) ALP (U/ L) Total Bilirubin (U/ L) Control 267 ± 62.31 105.0 ± 10.92 115 ± 14.52 0.23 ± 0.002 CCl4 treated Sham control a 567 ± 76.24** 283.0 ± 49.60 * 580 ± 56.44 ** 0.94 ± 0.12** Standard (Silymarin; 25 mg/kg) 303 ± 58.02 180.0 ± 13.34 156 ± 25.02 * 0.32 ± 0.045* mEPA (5 mg/ kg) 133 ± 31.70 * 106.0 ± 17.03 500 ± 45.10 0.65 ± 0.740 mEPA (10 mg/ kg) 132 ± 1.29 * 100.0 ± 27.95 * 375 ± 18.34 * 0.42 ± 0.009* mEPA (50 mg/ kg) 95 ± 44.16 ** 44.75 ± 3.30 * 150 ± 24.33 ** 0.25 ± 0.012** Fish oil (1 g/ kg) 205 ± 29.60 * 114.3 ± 4.35 * 149 ± 15.66 * 0.36 ± 0.301*

N = 6; Values are expressed in Mean ± SD a control group compared with sham control group; treated groups are compared with sham control group. * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001; **** p ≤ 0.0001. SGOT: Serum Glutamate Oxaloacetate Transaminase, SGPT: Serum Glutamate Pyruvate Transaminase, ALP: Alkaline Phosphatase

Table 2: Effect of mEPA, standard drug silymarin and fish oil on liver enzyme markers.