Time elapsed after initiation of treatment (weeks) |
Number of autopsid toads |
Number of affected toads |
Pathological changes |
Liver |
Fat body |
Ileum |
Stomach |
Kidney |
Testis |
2
4
6
8
10
12
14
16
18
20 |
4
8
12
13
8
12
10
9
12
12 |
0
0
3
4
2
2
3
2
2
4 |
0
0
0
0
1
1
1
2
0
3 |
0
0
1
0
0
0
1
0
1
1 |
0
0
1
1
0
0
0
0
0
0 |
0
0
1
1
0
0
0
0
0
0 |
0
0
0
0
1
0
1
0
1
0 |
0
0
0
2
0
0
0
1
0
0 |
Total |
100 |
22 |
8 |
4 |
2 |
2 |
3 |
3 |
Z value |
------ |
0.172 |
2.6107 * |
2.0203 * |
1.4213 |
1.421 |
1.745 |
1.745 |
|
* Significant at Z ≥ 1.96
No pathological changes were detected in the organs of any toad of the control groups during the experimental period and therefore they were not included in the table |
Table 2: Effect of administration fluconazole on the organs of the Egyptian toad (Bufo regularis). |