Treatment (mg/kg, p.o) % change in body weight
7th day 14th day 21st day 28th day 35th day 42nd day 45th day
Vehicle control +4.16 +7.33 +8.71 +12.87 +17.42 +21.59 +26.50
Pyridostigmine (20) +2.67 +6.25 +4.04 +4.15 +8.33 +8.33

+6.42

Pyridostigmine (30) +1.43 +0.94 +3.56 +2.45 +5.34 +5.83 +4.26
Pyridostigmine (45) -5.27 -6.82 -7.46 -10.40 -11.48 -14.05 -15.62
Table 2: Effect of daily oral administration of Pyridostigmine Bromide tablet up to 45 days on relative body weight of rats.