Table 4

Day	Pyrido-stigmine (mg/kg, p.o)	Hb (gm/dl) M ± SEM	RBC (10⁶/mm³) M ± SEM	WBC (10³/mm³) M ± SEM	Differential leukocyte count in % (M ± SEM)
Day	Pyrido-stigmine (mg/kg, p.o)	Hb (gm/dl) M ± SEM	RBC (10⁶/mm³) M ± SEM	WBC (10³/mm³) M ± SEM	N	L	E	B	M
0	control	12.70 ± 1.50	4.78 ± 0.13	5.02 ± 0.87	38.25 ± 2.27	52.28 ± 1.94	1.77 ± 0.07	1.57 ± 0.11	6.13 ± 0.88
	20	12.40 ± 1.84^ns	4.91± 0.85^ns	5.42 ± 0.23^ns	40.45 ± 2.45^ns	48.14 ± 1.62^ns	1.25 ± 0.11^ns	2.04 ± 0.01^ns	8.12 ± 0.67^ns
	30	12.82 ± 1.36^ns	5.75 ± 0.24^ns	5.18 ± 0.45^ns	44.09 ± 2.68^ns	46.61 ± 1.69^ns	2.40 ± 0.13^*	1.18 ± 0.02^ns	5.72 ± 0.93^ns
	45	13.15 ± 1.12^ns	5.91 ± 0.42^ns	5.09 ± 0.42^ns	42.13 ± 3.67^ns	46.70 ± 1.58^ns	2.52 ± 0.22^*	2.58 ± 0.58^ns	6.07 ± 0.50^ns
15	control	12.56 ± 1.97	5.11 ± 0.25	5.20 ± 0.79	40.22 ± 1.51	50.17 ± 1.60	1.98 ± 0.02	0.92 ± 0.14	6.71 ± 0.84
	20	13.42 ± 1.23^ns	5.78 ± 0.41^ns	8.32 ± 0.35^*	34.57 ± 2.30^ns	52.70 ± 3.97^ns	3.80 ± 0.27^ns	1.09 ± 0.22^ns	7.84 ± 0.97^ns
	30	11.08 ± 1.11^ns	4.72 ± 0.21^ns	8.97 ± 0.36^*	32.43 ± 2.39^ns	53.52 ± 2.11^ns	7.51 ± 0.32^***	1.44 ± 0.33^ns	5.10 ± 0.56^ns
	45	9.86 ± 1.14^ns	3.71 ± 0.20^**	9.34 ± 1.34^**	34.45 ± 3.12^ns	52.90 ± 4.22^ns	8.00 ± 0.97^***	1.22 ± 0.11^ns	3.43 ± 0.33^*
30	control	12.80 ± 1.56	5.45 ± 0.56	5.35 ± 0.78	39.24 ± 2.67	48.57 ± 1.55	1.26 ± 0.09	1.13 ± 0.01	9.80 ± 0.39
	20	11.50 ± 1.22^ns	4.55 ± 0.43^ns	8.95 ± 1.02^ns	31.08 ± 2.97^ns	52.93 ± 3.97^ns	5.32 ± 0.81^**	1.33 ± 0.03^ns	9.34 ± 0.49^ns
	30	9.83 ± 1.27^ns	4.10 ± 0.62^ns	9.76 ± 1.21^*	30.25 ± 2.17^ns	53.07 ± 4.97^ns	8.12 ± 0.94^***	1.05 ± 0.07^ns	8.51 ± 0.94^ns
	45	9.02 ± 1.31^ns	3.02 ± 0.55^*	10.94 ± 1.46^**	30.86 ± 4.07^ns	52.48 ± 3.84^ns	8.65 ± 1.05^***	1.30 ± 0.06^ns	6.71 ± 0.82^*
45	control	12.76 ± 1.23	5.29 ± 0.56	5.60 ± 0.41	37.62 ± 3.40	50.25 ± 1.90	2.14 ± 0.07	1.42 ± 0.03	8.93 ± 1.11
	20	9.34 ± 1.36^ns	3.83 ± 0.25^ns	9.35 ± 1.33^*	30.97 ± 2.67^ns	51.50 ± 3.43^ns	5.35 ± 0.97^*	1.58 ± 0.02^ns	10.60 ± 1.45^ns
	30	9.42 ± 1.99^ns	3.38 ± 0.62^ns	10.33 ± 1.17**	27.80 ± 2.53^ns	52.28 ± 3.27^ns	10.35 ± 1.09^***	1.45 ± 0.03^***	8.22 ± 1.06^ns
	45	8.09 ± 1.07*	3.04 ± 0.77*	10.90 ± 0.69**	27.03 ± 2.07*	54.44 ± 3.17^ns	10.45 ± 1.22^***	1.04 ± 0.07^***	7.04 ± 1.02^ns

n=10. ^*P<0.05, ^**P<0.01, ^***P<0.001 and ^ns=not significant when compared to respective control group

Table 4: Effect of daily oral administration of Pyridostigmine Bromide tablet up to 45 days on peripheral blood parameters of rats.