Iron isomaltoside 1000 IV bolus doses
100 mg 200 mg 500 mg
Mean (SD) Geometric mean Mean (SD) Geometric mean Mean (SD) Geometric mean
AUC0-t  (mg h/dL) 3.21 (1.17) 2.99 6.73 (2.48) 6.26 14.80(3.99) 14.34
AUC (mg h/dL) 4.69 (2.74) 4.00 9.44 (4.50) 8.54 19.51 (6.92) 18.61
Cmax(mcg/dL) 101(23) 99 210 (60) 202 507 (175) 484
Tmax (h) 1.42 (1.39) 1.00 1.35 (1.43) 0.91 0.59 (0.22) 0.57
Ke (1/h) 0.0273 (0.0144) 0.0240 0.0266 (0.0186) 0.0226 0.0230 (0.0058) 0.0223
T1/2  (h) 33.07 (18.99) 28.86 35.14 (18.10) 30.72 32.35 (10.68) 31.14
Table 2: Pharmacokinetic parameters by treatment group for total s-iron.