| Drugs |
% F |
Urinary excretion % |
Plasma Protein Binding % |
Cl (ml/min/ kg) |
Vd (liters/kg) |
Half-life
(hr) |
| Gemfibrozil |
98 ± 1 |
< 1 |
> 97 |
1.7 ± 0.4 |
0.14 ± 0.03 |
1.1 ± 0.02 |
| Lovastatin |
< 5 |
Negligible |
95 |
4-18 |
- |
1.1-1.7 |
| Pravastatin |
18 ± 8 |
47 ± 7 |
43-48 |
3.5 ± 2.4 |
0.46 ± 0.04 |
1.8 ± 0.8 |
| Simvastatin |
< 5 |
Negligible |
94 |
7.6 |
- |
1.9 |
| Clofibrate |
95 ± 10 |
57 ± 2 .1 |
96.5 ± 0.3 |
0.12 ±.01 |
0.11 ± 0.02 |
13 ± 3 |
|
