MIII
  Pearson, r (p) Spearman, rs (p)
P450 0.61 (0.014*) 0.525 (0.045*)
b5 0.076 (0.78) 0.039 (0.88)
CYP1A2 0.395 (0.14) 0.209 (0.454)
CYP2A6 0.579 (0.024*) 0.545 (0.036*)
CYP2B6 0.565 (0.028*) 0.489 (0.064)
CYP2C8 0.234 (0.40) 0.227 (0.41)
CYP2C9 0.027 (0.92) 0.136 (0.629)
CYP2C19 0.469 (0.078) 0.246 (0.376)
CYP2D6 -0.577(0.024*) -0.543 (0.036*)
CYP2E1 -0.073 (0.79) -0.068 (0.80)
CYP3A 0.837 (0.0001*) 0.785 (0.001*)
CYP4A11 -0.062 (0.82) -0.045 (0.874)
Table 1: Correlation between the formation rate of MIII from 17-hydroexemestane and individual P450 isoform-specific activities in a panel of well characterized HLMs.