Parameters Group I Group II Group III
Body weight (g) 224.75 ± 29.40 159.6 ± 13.11a 202.5 ± 31.81b
Feed weight (g) 60.71 ± 7.77 49.2 ± 5.76b 63.86 ± 8.10a
Organs weight (g)      
Liver 5.81 ± 0.50 8.50 ± 0.56a 6.15 ± 0.21a
Kidney 1.32 ± 0.09 1.07 ± 0.04a 1.25 ± 0.15b
Spleen 0.591 ± 0.03 0.724 ± 0.14b 0.600 ± 0.08c
Relative organ weight (%)      
Liver 2.63 ± 0.52 5.54 ± 0.42a 3.05 ± 0.35a
Kidney 0.73 ± 0.15 0.67 ± 0.05ns 0.72 ± 0.11ns
Spleen 0.27 ± 0.05 0.45 ± 0.07a 0.3 ± 0.10b
All data are mean ± SD of each group of 10 animals. One-way analysis of variance (ANOVA) followed by Newman-Keuls comparison test are used to determine statistical difference between control (group I) vs paracetamol (PCM) induced hepatotoxicity group(group II) and paracetamol (PCM) induced hepatotoxicity group (group II) vs livartho treated group (group III). Where
a ; p<0.0001(highlysignificant) b ; p<0.001(significant) c; p <0.01 (significant). d; p<0.05 (significant). The p-values >0.05 were considered statistically non-significant.
Table1: Status of body weight (g), feed intake (g), organ weight (g) and relative organ weight (%) in PCM induced hepatic damage and Livartho treated groups.