Parameters Group I Group II Group III
Hb (g/dL) 14.15 ± 3.0 11.68 ± 2.1a 14.88 ± .699b
RBC (1012/L) 6.4 ± 0.61 5.30 ± 1.05c 6.31 ± 0.98c
WBC(109/L) 18.87 ± 1.67 12.53 ± 2.05a 17.0 ± 2.87a
PCV (%) 37.25 ± 2.33 30.2 ± 5.43b 36.75 ± 2.61b
MCH (pg) 23.175 ± 1.32 22.12 ± 0.85d 24.20 ± 1.42a
MCV(fL) 58.45 ± 2.83 57.14 ± 3.86Ns 61.75 ± 1.70a
Platelet (109/L) 755 ± 53 499.6 ± 159a 736.5 ± 108.4a
All data are mean ± SD of each group of 10 animals. One-way analysis of variance (ANOVA) followed by Newman-Keuls comparison test are used to determine statistical difference between control (group I) vs paracetamol (PCM) induced hepatotoxicity group(group II) and paracetamol (PCM) induced hepatotoxicity group (group II) vs livartho treated group (group III). Where
a; p< 0.0001(highly significant) b; p < 0.001(significant) c; p < 0.01(significant). d; p< 0.05 (significant). The p-values >0.05 were considered statistically non-significant.
Table 2: Status of hematological parameters in PCM induced hepatotoxicity and Livartho treated groups.