| Parameters |
Group I |
Group II |
Group III |
| Hb (g/dL) |
14.15 ± 3.0 |
11.68 ± 2.1a |
14.88 ± .699b |
| RBC (1012/L) |
6.4 ± 0.61 |
5.30 ± 1.05c |
6.31 ± 0.98c |
| WBC(109/L) |
18.87 ± 1.67 |
12.53 ± 2.05a |
17.0 ± 2.87a |
| PCV (%) |
37.25 ± 2.33 |
30.2 ± 5.43b |
36.75 ± 2.61b |
| MCH (pg) |
23.175 ± 1.32 |
22.12 ± 0.85d |
24.20 ± 1.42a |
| MCV(fL) |
58.45 ± 2.83 |
57.14 ± 3.86Ns |
61.75 ± 1.70a |
| Platelet (109/L) |
755 ± 53 |
499.6 ± 159a |
736.5 ± 108.4a |
All data are mean ± SD of each group of 10 animals. One-way analysis of variance
(ANOVA) followed by Newman-Keuls comparison test are used to determine
statistical difference between control (group I) vs paracetamol (PCM) induced
hepatotoxicity group(group II) and paracetamol (PCM) induced hepatotoxicity
group (group II) vs livartho treated group (group III). Where
a; p< 0.0001(highly
significant) b; p < 0.001(significant) c; p < 0.01(significant). d; p< 0.05 (significant).
The p-values >0.05 were considered statistically non-significant. |
