Parameters Group I Group II Group III
SGOT (IU/L) 140 ± 10.61 217.3 ± 55.2a 155.8 ± 7.77b
SGPT (IU/L) 48.5 ± 3.0 67.5 ± 7.5a 57.75 ± 9.9c
LDH (IU/L) 403.5 ± 85.9 755.5 ± 156.8a 261.75 ± 56.6a
Total bilirubin (mg/dL) 0.813 ± .212 1.647 ± 0.2a 0.433 ± 0.03a
Cholestrol (mg/dL) 61.33 ± .212 78.0 ± 5.58a 63.25 ± 8.89a
TGA (mg/dL) 66.5 ± 3.59 143.7 ± 50.2a 107.75 ± 12.3c
Protein (mg/dL) 7.85 ± 0.778 4.5 ± 0.212a 7.25 ± 0.778a
Albumin (mg/dL) 3.475 ± 0.299 2.02 ± 0.636a 3.3 ± 0.212a
All data are mean ± SD of each group of 10 animals. One-way analysis of variance (ANOVA) followed by Newman-Keuls comparison test are used to determine statistical difference between control (group I) vs paracetamol (PCM) induced hepatotoxicity group(group II) and paracetamol (PCM) induced hepatotoxicity group (group II) vs livartho treated group (group III). Where a; p< 0.0001(highly significant) b ; p < 0.001( significant) c; p < 0.01( significant). d ; p< 0.05 (significant). The p-values >0.05 were considered statistically non-significant.
Table 3: Status of biochemical parameters in PCM induced hepatotoxicity and Livartho treated groups.