Figure 3: Changes in F/f curves in the endotoxin-only injection (a) and in the ICS or LABA inhalation plus endotoxin injection groups (b). The F/f curves significantly shifted downward at E4 (###, p<0.001) compared with those of the E-sham. *p<0.05, **p<0.01, ***p<0.01 compared with each frequency in the E-sham. The F/f curves at ICSE4 (#, p<0.05) and LABAE4 significantly shifted upward (##, p<0.01) compared with those of the EL-sham. *p<0.05, **p<0.01 compared with each frequency in the EL-sham.