Figure 1: Chronic insulin treatment potentiates IL-6(20ng/ml)-induced vascular smooth muscle cell migration. Cells were pretreated with 5nM of insulin for 24 hours followed by stimulation with 20ng/ml of interlukin-6 for 24 hours in presence and absence of 5nM of insulin. The migration distance before and after IL-6 treatment was measured and expressed as Ám/24hrs, mean+SE. Results are from three independent experiments. Data are analyzed by using one-way ANOVA followed by post hoc test. *P<0.05, compared to control, #p<0.05 compared to IL-6 alone.