All
(n=69)
Normal
(n=34)
High AUCinsulin (n=15) High AUCglucose (n=20)
Gender, Male n (%) 32 (46%) 17 (50%) 8 (53%) 8 (40%)
AGE (yrs) 42.0 ± 9.0 40.5 ± 8.5 41.5 ± 10.3 44.9 ± 8.5
BMI (kg.m-2) 28.1 ± 5.0 27.5 ± 4.2 26.6 ± 3.9 30.2 ± 5.8
 SBP (mmHg) 121.5 ± 10.6 119 ± 11.9 122.1 ± 10.0 125.6 ± 7.6
DBP (mmHg) 79.6 ± 6.4 78.4 ± 7.0 79.1 ± 6.1 82.1 ± 5.1
FPG (mmol/l)*# 4.2 ± 0.8 4.2 ± 0.7 4.9 ± 0.9 4.1±0.9
2hPG (mmol/l)* 5.6 ± 1.8 5.5 ± 0.9 5.6 ± 0.9 5.8 ± 0.9
HbA1C(%)*# 5.9±0.5 5.7 ± 0.4 5.7 ± 0.5 6.2 ± 0.6a
Total cholesterol* mg/dl 192.1±32.5 186 ± 32.1 189 ± 37.5 204.5 ± 27.1
HDL-C* mg/dl 44.2±9.1 43.9 ± 9.1 41.6 ± 11.7 46.6 ± 6.4
LDL-C* mg/dl 123.7±32.4 115.6 ± 34 125.3 ± 30.8 136.1 ± 27.9
Triglycerides* mg/dl 153.6±85.5 150.6 ± 82.4 146.7 ± 87.6 163.9 ± 92.5
1st degree family history of diabetes n (%) 63(91%) 30 (88%) 13 (87%) 20 (100%)
# p<0.05 for global comparison
*Measurements performed at T0 (all other measurements were performed at T8
Normal: AUCglucose < 960 mmol/l.mn and AUCinsulin <= 75500 pmol/l.mn ; High isolated AUCglucose >= 960 mmol/ l.mnl and AUCinsulin <= 7 5500 pmol/ l.mn; High AUCinsulin >
75500 pmol/ l.mn
a – Compared with normal
Table 2: Characteristics of patients at T0 and T8 classified according to plasma insulin and glucose during FSOGTT at T8.