Characteristics Low GPx activity (n=34) High GPx activity (n=25) P value Beta value 1 -Beta (%)
Age (years) 56 ± 1 56 ± 1 0.92 0.03 97
Body weight (kg) 91 ± 2 91 ± 3 1.00 0.03 97
BMI (kg/m2) 34.5 ± 0.5 34.6 ± 0.6 0.85 0.03 97
Systolic BP (mm Hg) 125 ± 3 126 ± 3 0.73 0.04 96
Diastolic BP (mm Hg) 79 ± 3 79 ± 1 0.96 0.03 97
Blood lipids and apolipoproteins          
Cholesterol (mmol/L) 5.21 ± 0.15 5.57 ± 0.18 0.13 0.66 34
LDL-C (mmol/L)1 3.09 ± 0.14 3.41 ± 0.17 0.15 0.56 44
HDL-C (mmol/L) 1.52 ± 0.05 1.48 ± 0.06 0.67 0.08 92
Triglycerides (mmol/L)1 1.30 ± 0.09 1.32 ± 0.09 0.33 0.04 96
apoB (g/L) 0.89 ± 0.04 1.02 ± 0.03 0.02    
Glucose status          
Fasting glycemia (mmol/L) 5.4 ± 0.1 5.7 ± 0.1 0.13 0.80 20
Fasting insulinemia (µU/mL)2 16.1 ± 1.2 17.7 ± 1.6 0.41 0.15 85
HOMA-IR 3.48 ± 0.29 4.83 ± 0.60 0.04    
Liver insulin resistance index (x104) 29.3 ± 2.4 39.0 ± 4.0 0.03    
SIisOGTT 0.263 ± 0.003 0.257 ± 0.004 0.18 0.34 66
Glucose disposal (mg/min/kg) 12.5 ± 0.7 11.6 ± 0.9 0.38 0.16 84
Serum inflammatory markers          
IL-6 (pg/mL) 1.7 ± 0.2 1.6 ± 0.7 0.65 0.04 94
hsCRP (mg/L)3 4.4 ± 0.5 4.4 ± 0.6 0.94 0.03 97
Orosomucoid (g/L) 0.87 ± 0.02 0.87 ± 0.04 0.93 0.03 97
Haptoglobin (g/L) 1.6 ± 0.1 1.5 ± 0.1 0.46 0.11 89
Mean ± SEM
BMI: body mass index, BP: blood pressure, LDL-C: low density lipoprotein cholesterol, HDL-C: high density lipoprotein cholesterol, apoB: apolipoprotein B, glucose disposal
rate calculated from the hyperinsulinemic euglycemic clamp, hsCRP: high sensitivity C-reactive protein
1whole cohort: n=58, Low GPx activity: n=34, High GPx activity: n=24
2whole cohort: n=57, Low GPx activity: n=32, High GPx activity: n=25
3whole cohort: n=48, Low GPx activity: n=25, High GPx activity: n=23
Table 2: Anthropometric, blood pressure, blood lipid profile, glucose status and inflammatory markers of subjects with either low or high GPx activity.