Treatment Total receptor molecules / total insulin molecules No. receptor molecules per molecule of insulin
Males
Control 29 x1017/ 0.188 x1012 153 x105a
10% FGS 121x1017/ 0.088 x1012 1373 x105b
2.5% SDF 306 x1017/ 0.088 x1012 3491x105b
20% FGS 216 x1017/ 0.038 x1012 5765 x105b
5% SDF 573 x1017/ 0.053 x1012 10839 x105b
Females
Control 23 x1017/ 0.727 x1012 31 x105a
10% FGS 152 x1017/ 0.279 x1012 544 x105b
2.5% SDF 454 x1017/ 0.109 x1012 4189 x105b
20% FGS 234 x1017 / 0.049 x1012 4803 x105b
5% SDF 388 x1017 / 0.063 x1012 6159 x105b
Each group consists of 6 males and 5 females. Values bearing different superscripts i.e. ‘a’ and ‘b’ are statistically different by Duncan’s multiple range test at p<0.05 for males and females respectively. Treatment with both the levels of SDF or FGS in the diet for nine weeks to obese rats showed a significant (p<0.05) increase in insulin receptors per molecule of insulin in all the experimental rats compared to control rats. FGS: Fenugreek seeds; SDF: Soluble dietary fiber
Table 5: Insulin sensitivity and resistance index: expressed as a ratio of number of receptors on erythrocytes per molecule of insulin in plasma of obese rats at the end of 9 weeks.