Treatment Plasma glucose (mg/dl) C 83.46± 7.95ab D 223.49 ± 2.93 LevD 240.0± 2.02 LevDG 274.3 ± 19.96 a LevDM 321.6± 8.09 a LevDI20 257.0± 32.9 LevDI40 194.4± 5.17b Values are mean ± SEM. (n=5 per group). abp<0.0001 and ap<0.05 significantly higher than the diabetic group and bp<0.05 significantly lower than the diabetic group. C: Control group D: Diabetic group LevD: Potassium channel activated diabetic group LevDG: Potassium channel activated diabetic group treated with glibenclamide LevDM: Potassium channel activated diabetic group treated with metformin LevDI20: Potassium channel activated diabetic group treated with 20 i.u/kg insulin LevDI40 : Potassium channel activated diabetic group treated with 40 i.u/kg insulin

Table 3: The effects of levcromakalim on the plasma glucose of streptozotocininduced diabetic rats treated with glibenclamide (5 mg/kg), metformin (350 mg/ kg) and insulin (5 & 10 i.u/kg).