Treatment Plasma glucose (mg/dl)
C 83.46± 7.95ab
D 223.49 ± 2.93
LevD 240.0± 2.02
LevDG 274.3 ± 19.96 a
LevDM 321.6± 8.09 a
LevDI20 257.0± 32.9
LevDI40 194.4± 5.17b
Values are mean ± SEM.
(n=5 per group).
abp<0.0001 and ap<0.05 significantly higher than the diabetic group and bp<0.05
significantly lower than the diabetic group.
C: Control group
D: Diabetic group
LevD: Potassium channel activated diabetic group
LevDG: Potassium channel activated diabetic group treated with glibenclamide
LevDM: Potassium channel activated diabetic group treated with metformin
LevDI20: Potassium channel activated diabetic group treated with 20 i.u/kg insulin
LevDI40 : Potassium channel activated diabetic group treated with 40 i.u/kg insulin
Table 3: The effects of levcromakalim on the plasma glucose of streptozotocininduced diabetic rats treated with glibenclamide (5 mg/kg), metformin (350 mg/ kg) and insulin (5 & 10 i.u/kg).