Multivariate (adjusted) regression coefficient  
  n Estimate 95% CI P value
Index treatment        
Detemir 298 0 Reference  
Glargine 708 –0.17 (–0.31, –0.02) <0.05
         
Covariates        
Age, years 1006 –0.01 (–0.01, 0.00) <0.001
Gender        
Male 548 0 Reference
Female 458 0.13 (0.00, 0.26) 0.06
Start year        
2004 255 0 Reference
2005 263 0.06 (–0.12, 0.24) 0.54
2006 210 –0.14 (–0.34, 0.05) 0.15
2007 278 0.27 (0.08, 0.45) <0.01
Prescriber        
General practitioner 494 0 Reference
Specialist 512 –0.16 (–0.29, –0.03) <0.05
Prior anti-diabetics usea        
Insulin 225 0.69 (0.52, 0.85) <0.001
Baseline HbA1c (%) 1006 –0.60 (–0.65, –0.55) <0.001
aBased on drug dispensings in the year before cohort entry date.
Table 3: Multivariate regression of HbA1c reductions in patients with type 2 diabetes mellitus treated with glargine or detemir.