| |
Multivariate (adjusted)
regression coefficient |
|
| |
n |
Estimate |
95% CI |
P value |
| Index treatment |
|
|
|
|
| Detemir |
298 |
0 |
Reference |
|
| Glargine |
708 |
–0.17 |
(–0.31, –0.02) |
<0.05 |
| |
|
|
|
|
| Covariates |
|
|
|
|
| Age, years |
1006 |
–0.01 |
(–0.01, 0.00) |
<0.001 |
| Gender |
|
|
|
|
| Male |
548 |
0 |
Reference |
– |
| Female |
458 |
0.13 |
(0.00, 0.26) |
0.06 |
| Start year |
|
|
|
|
| 2004 |
255 |
0 |
Reference |
– |
| 2005 |
263 |
0.06 |
(–0.12, 0.24) |
0.54 |
| 2006 |
210 |
–0.14 |
(–0.34, 0.05) |
0.15 |
| 2007 |
278 |
0.27 |
(0.08, 0.45) |
<0.01 |
| Prescriber |
|
|
|
|
| General practitioner |
494 |
0 |
Reference |
– |
| Specialist |
512 |
–0.16 |
(–0.29, –0.03) |
<0.05 |
| Prior anti-diabetics usea |
|
|
|
|
| Insulin |
225 |
0.69 |
(0.52, 0.85) |
<0.001 |
| Baseline HbA1c (%) |
1006 |
–0.60 |
(–0.65, –0.55) |
<0.001 |
aBased on drug dispensings in the year before cohort entry date. |
