Figure 4: PKCβ immunostaining in normal and diabetic Psammomys retinas. In ND retinas, residual staining with PKCβ antibody was visible in the synapses (B) but in HDD retinas, PKC β antibody showed clear staining in cell bodies within the inner nuclear layer (INL), as well as their axons and synaptic endings in the inner plexiform layer (IPL), corresponding to rod and cone ON bipolar cells D). Bar in D=80 μm for all panels.
Abbreviation: GCL: Ganglion Cell Layer; INL: Inner Nuclear Layer; IPL: Inner Plexiform Layer; ONL: Outer Nuclear Layer; OPL: Outer Plexiform Layer; OS: Outer Segments; ND: Natural Diet; HDD: High-protein Diet Diabetic.