Figure 1: Cluster analysis on microarray data. Hierarchical clustering was performed on differentially expressed genes for the following treatments: (A) diabeticlike environment (200 μg/ml AGE-HSA and 250 mg/dl glucose) vs. control (100 μg/ml HSA and 100 mg/dl glucose), (B) Diabetic environment and 10-10 mol/l calcitriol treatment vs. diabetic environment only (200 μg/ml AGE-HSA and 250 mg/dl glucose). Enriched biological pathways represented by the differentially expressed genes are suggested. (C) Venn diagram representing common and unique differentially expressed genes regulated by a diabetic-like environment (AGE+G) and diabetic-like environment plus 10-10 mol/l calcitriol (AGE+G+C).