Group IControl Group (n=39) Group IIPCOS Group (n=44) P
Age (years) 27.5 ± 3.94 26.79 ± 3.66 NS
Age at menarche (years) 12.48 ± 1.23 11.75 ± 1.71 <0.05#
Oligo-/amenorrhea+/- 0/39 44/0 <0.001#
Hirsutism +/− 0/39 35/9 <0.001#
PCOS on TVU+/− ND 41/3 <0.001#
Familial history +/− 4/35 14/30 <0.05#
BMI (kg ⁄m2) 29.85 ± 2.64 30.95 ± 4.07 NS
WC (cm) 95.33 ± 10.57 97.39 ± 15.37 NS
HC (cm) 109.4 ± 9.96 113.79 ± 13.06 NS
WHR 0.87± 0.05 0.85 ± 0.06 NS
SBP (mmHg) 113.25 ± 5.72 113.02 ± 7.41 NS
DBP (mmHg) 73.25 ± 6.16 74.65 ± 6.58 NS
FSH (U/L) 4.9 ± 1.09 4.72 ± 1.22 NS
LH (U/L) 4.71 (3.8-6.07) 8.31 (6.4-9.37) <0.001**
Testosterone (ng/ml) 0.8 ± 0.32 1.29 ± 0.34 <0.001*
FBG (mg/dl) 90.14 ± 9.84 107.49 ± 10.89 <0.001*
FI (uIU/ml) 14.03 ± 4.47 22.52 ± 4.65 <0.001*
GIR 6.99 ± 1.98 5.49 ± 1.53 <0.001*
HOMA-IR 3.17 (2.17-4.23) 5.73 (4.92-7.39) <0.001**
QUICKI 0.326 ± 0.017 0.297± 0.01 <0.001*
sCD40L (ng/ml) 0.82 (0.43-1.26) 2.46 (1.08-4.16) <0.001**
PCOS: Polycystic Ovary Syndrome; TVU: Trans-Vaginautrrasonography; BMI: Body Mass Index; WC: Waist Circumference; HC: Hip Circumference; WHR: Waist-To- Hip Ratio; SBP: Systolic Blood Pressure; DBP: Diastolic Blood Pressure; FSH: Follicle Stimulating Hormone; LH: Luteinizing Hormone; FBG: Fasting Blood Glucose; FI: Fasting Serum Insulin; GIR: Glucose-To-Insulin Ratio; HOMA-IR: Homeostatic Model Assessment for IR; QUICKI: Quantitative Insulin Sensitivity Check Index; Scd40l: Soluble CD40L. Values were expressed as Mean ± Standard Deviation [SD] (for normally distributed data), Median and Interquartile range (for non-normally distributed data), or number (for categorical data). *Analysis using independent student’s T-test, **Analysis using Mann-Whitney’s U-test, #Analysis uing chi-squared (χ2) Test; NS: Non-Significant
Table 1: Demographic data, anthropometric measures and biochemical variables of the studied groups.