Figure 1: Environmental-Scanning Electron Microscopy (E-SEM) images of co-cultures of Raw 264.7 macrophages and UMR-106 osteoblastic cells. Left: Image showing a dark giant cell (osteoclast) and smaller high-contrast Raw 264.7 cells (1400x). Middle: Magnification of the same image showing the osteoclast (3000x). Right: Osteoclast stained by TRAP cytochemistry (Obj. 40x).