Age of diagnosis seems to be confined to adulthood. |
Presence of HLA-DR3/DR4 and HLA-DR2 is low-moderate. |
Anti-GAD65 is the marker of choice, but IA-IA2 antibodies can also be detected. |
Plasma insulin is usually low with absent ketosis. |
Insulin resistance presence is variable, and it´s considered a major role in the pathogenesis. |
Diagnosis of Metabolic Syndrome is variable. |
Body Mass Index is normal or high. |
Initial treatment suggested is insulin, along with oral antihyperglycemic agents such as Metformin or Thiazolidinediones when appropiate. |