SNP (genotype) Cases (%) Controls (%) P-value
-1722 (TT/TC/CC) 282 (71) 105 (27) 9 (0.03) 318 (0.80) 74 (19) 4 (1) 0.084
-1661 (AA/AG/GG) 159 (40) 185 (47) 52 (13) 208 (53) 158 (40) 30 (7) 0.0098*
-651 (CC/CT/TT) 318 (80) 78 (20) 0 (0) 343 (86) 50 (13) 3 (1) 0.112
-318 (CC/CT/TT) 325 (82) 67 (17) 4 (1) 347 (88) 49 (12) 0 (0) 0.84
49 (AA/AG/GG) 157 (40) 184 (46) 55 (0.14) 211 (53) 154 (39) 31 (8) 0.0028*
-819 (CC/CT/TT) 181 (46) 178 (45) 37 (9) 214 (54) 164 (41) 18 (5) 0.098
+6230 (AA/AG/GG) 76 (19) 195 (49) 125 (32) 107 (27) 195 (49) 94 (24) 0.112
The table shows counts and percentages between brackets of the genotypes of seven CTLA-4 SNPs studied.
P-values are corrected for multiple testing of seven SNPs
Table 5: Genotype association.