Characteristics Adjusted odds ratio for any Macro-vascular Disease P value (adjusted analysis) Adjusted odds ratio for Ischaemic heart Disease P value (adjusted analysis) Adjusted odds ratio for cerebro-vascular Disease P value (adjusted analysis) Adjusted odds ratio for peripheral vascular disease P value (adjusted analysis) Age 1.04 (1.02-1.07) 0.001 1.03 (1.00-1.06) 0.023 1.04 (1.00-1.08) 0.036 1.02 (0.99-1.06) 0.176 Gender Female 1   1   1   1   Male 1.17 (0.89-1.54) 0.271 0.99 (0.73-1.34) 0.954 1.51 (0.94-2.42) 0.086 1.06 (0.72-1.56) 0.778 Smoking Non smoker 1   1   1   1   Smoker or Ex-smoker 1.41 (1.06-1.87) 0.019 1.40 (1.02-1.91) 0.037 0.90 (0.57-1.44) 0.668 1.88 (1.23-2.86) 0.003 Duration of diabetes 1.20 (1.06-1.36) 0.003 1.17 (1.03-1.34) 0.02 1.14 (0.93-1.41) 0.217 1.22 (1.02-1.45) 0.029 Mean HbA1c 1.16 (1.05-1.30) 0.006 1.12 (1.00-1.26) 0.049 1.28 (1.09-1.50) 0.003 1.14 (0.99-1.31) 0.078 Hypertension 1.26 (0.95-1.66) 0.107 1.20 (0.88-1.63) 0.243 1.09 (0.68-1.74) 0.718 1.79 (1.18-2.71) 0.006

Table 2: Adjusted odds ratio for risk factors associated with the presence of macro-vascular disease in elderly patients with type 1 diabetes