Lifestyle risk factors
(risk factor B) |
No. Cases |
Person-years |
HR a (95% CI)
FHD but not risk factor B |
HR a (95% CI)
Risk factor B but not FHD |
HR a (95% CI)
FHD and
risk factor B |
SI
(95% CI) |
AP
(95% CI) |
Overweight (25 ≤ BMI<30) |
47 |
323,793 |
2.23 (1.00-4.99) |
1.38 (0.65-2.94) |
4.60 (2.32-9.10) |
2.23 (0.70-7.04) |
0.43 (0.03-0.83) |
Obesity (30 ≤ BMI) |
48 |
90,072 |
2.16 (0.97-4.84) |
6.69 (3.25-13.77) |
11.68 (5.68-24.01) |
1.56 (0.81-3.01) |
0.33 (0.00-0.72) |
WHR (at risk)b |
18 |
69,193 |
2.15 (0.86-5.35) |
1.84 (0.61-5.55) |
5.75 (2.24-14.74) |
2.39 (0.63-9.08) |
0.48 (0.01-0.95) |
Physical inactivity |
74 |
484,696 |
2.13 (1.31-3.45) |
1.28 (0.71-2.28) |
3.62 (2.13-6.14) |
1.85 (0.74-4.67) |
0.33 (0.00-0.71) |
Non-regular alcohol consumption |
73 |
299,414 |
2.40 (1.33-4.33) |
1.32 (0.70-2.51) |
3.68 (2.02-6.70) |
1.56 (0.64-3.79) |
0.26 (0.00-0.69) |
Low psychosocial well-being |
22 |
80,490 |
1.58 (0.90-2.76) |
1.53 (0.69-3.42) |
5.03 (2.56-9.89) |
3.63 (0.86-15.25) |
0.58 (0.24-0.93) |
SI: Synergy Index; AP: Attributable Proportion
Total study population: N=49,712.
aAll combinations adjusted for age and sex; smoking, education, physical activity, and BMI (except the factor under analyses)
bResults from HUNT2 to HUNT3 (1995-2008) |