Outcome Adjusteda regression coefficient or odds ratio (95%CI) p
Mean blood glucose during the first 120 hours
Mean blood glucose (mmol/L) -0.53 (-1.28, 0.22)b 0.163
Glycaemic range during the first 120 hours
Hyperglycaemic range (7.0 mmol/L) -5.73 (-14.8, 3.35)b 0.214
Hypoglycaemic range (4.0 mmol/L) -0.82 (0.79, -2.43)b 0.313
Glucose variability during the first 120 hours
Variability during the first 120 hours -1.28 (1.27, -3.83)b 0.322
Hypoglycaemia during the first 120 hours
Mild hypoglycaemia (2.5-3.8 mmol/L) 0.59 (0.27, 1.29)c 0.187
Severe hypoglycaemia (<2.5mmol/L) 0.33 (0.03, 3.75)c 0.375
Hospital outcomes
Ward length-of-stay (days) -1.62 (-3.63, 0.40)b 0.114
In-hospital mortality 0.39 (0.04, 3.58)c 0.406
Transfer to ICU 0.35 (0.03, 3.99)c 0.397
BMI: Body-Mass Index; ICU: Intensive Care Unit; LRTI: Lower Respiratory Tract Infection
aAdjusted for diabetes type and time since diabetes diagnosis, BMI, presence of dyslipidaemia, admission blood glucose concentration, chronic therapy at admission (metformin, insulin), and main hospital diagnosis (LRTI or acute cardiac condition).
bAdjusted regression coefficient.
cAdjusted odds ratio.
Table 3: Primary and secondary outcomes: adjusted regression coefficient or odds ratio for iSSC group relative to historical control group