Allele/Genotype T1D Patients N=250 ControlsN=480 T1D vs. Controls   n % n % p Odds Ratio 95% C.I. Allele1858C 473 94.6 941 98.02 0.0004 0.35 0.18-0.67 Allele1858T 27 5.4 19 1.98 0.0004 2.82 1.49-5.4 Genotype CC 223 89.2 461 96.04 0.0003 0.34 0.18-0.65 Genotype CT 27 10.8 19 3.96 0.0003 2.93 1.53-5.71

Table 1: Allele and genotype frequencies of PTPN22 C1858T in T1D as compared to normal healthy controls.