| Allele/Genotype |
T1D Male N=144 |
T1D Female N=106 |
Controls Male N=345 |
Controls Female N=135 |
Male T1Dvs. Male Controls |
Female T1Dvs. Female Controls |
| |
n(%) |
n(%) |
n(%) |
n(%) |
p value |
Odds Ratio |
95% C.I. |
p value |
Odds Ratio |
95% C.I. |
| Allele1858C |
272 (94.4) |
201
(94.8) |
673
(97.5) |
268
(99.25) |
0.015 |
0.43 |
0.2-0.9 |
0.003* |
0.16** |
0.06-0.43 |
| Allele1858T |
16
(5.6) |
11
(5.2) |
17
(2.5) |
2
(0.75) |
0.015 |
2.33 |
1.08-4.97 |
0.003* |
6.12** |
2.3-16.26 |
| Genotype CC |
128 (88.9) |
95
(89.6) |
328
(96.1) |
133
(98.5) |
0.013 |
0.41 |
0.19-0.9 |
0.002* |
0.15** |
0.05-0.42 |
| Genotype CT |
16
(11.1) |
11
(10.4) |
17
(4.9) |
2
(1.5) |
0.013 |
2.4 |
1.1-5.2 |
0.002* |
6.4** |
2.4-17.2 |
*Fisher’s exact test was used to calculate p values.
**Haldane’s modification was used to calculate the Odds Ratio. |
