Allele/Genotype T1D Patients N=243 ControlsN=327 p Odds Ratio 95% C.I.
  n % n %      
DRB1*03:01 188 77.4 52 15.9 6.58 × 10-49 18.07 11.61-28.21
DRB1*04:01 28 11.5 8 2.45 0.00001 5.19 2.24-13.4
DRB1*04:03 8 3.29 29 8.87 0.0075 0.35 0.13-0.8
DRB1*04:05 22 9.05 1 0.31 5.71 × 10-8* 22.11** 6.82-71.59
DRB1*07:01 30 12.35 103 31.5 8.96 × 10-8 0.31 0.19-0.49
* Fisher’s exact test was used to calculate p values.
** Haldane’s modification was used to calculate the Odds Ratio.
Table 4: Frequencies of predisposing HLA-DRB1 alleles In T1D patients and controls typed for PTPN22 C1858T.