|
Ki Value (nM) |
| Rat SGLT1 |
Rat SGLT2 |
| Sergliflozinetabonate |
3350 ± 110 |
651 ± 149 |
| Sergliflozin |
704 ± 254 |
17.1 ± 2.6 |
| Phlorizin |
275 ± 153 |
41.8 ± 11.4 |
Data are presented as means ± S.E.M. from 3 experiments. An AMG uptake
experiment was performed with COS-7 cells transiently transfected with rat SGLT1
or SGLT2, and the Ki values for each SGLT were calculated [20]. |
