IC50 (nM)
Compound
hSGLT1
hSGLT2
GLUT1
UGE
a
(mg/day)
Canagliflozin
910
2.2
>10000
3696
Table 4:
hSGLT1, hSGLT2, Facilitated Glucose Transporter 1 (GLUT1) Inhibitory
Activity, and Rat Urinary Glucose Excretion (UGE) Data for Canagliflozin [41].
