All patients Normal weight Overweight/ obese P-value No MetS MetS  P-value
N (%) 418 90 (22) 328 (78)   179 (43) 239 (57)  
Age, years 55.2 ± 11.3 55.8 ± 13.0 55.1 ± 10.8 0.59 53.7 ± 10.3 56.3 ± 10.3 0.021
Gender, males/females 239/179 49/41 190/138 0.55 91/88 148/91 0.023
Weight, kg 85 ± 19 66 ± 9 90 ± 18 <0.001 77 ± 17 91 ± 19 <0.001
Height, cm 169 ± 10 168 ± 10 169 ± 11 0.64 168 ± 10 169 ± 11 0.2
BMI, kg/m2 29.7 ± 6.2 22.7 ± 2.1 31.6 ± 5.5 <0.001 27.1 ± 5.8 31.7 ± 5.8 <0.001
Mean blood pressure, mmHg 109 ± 15 105 ± 15 110 ± 15 0.018 105 ± 15 111 ± 15 <0.001
Total cholesterol, mg/dL 214 ± 46 209 ± 48 216 ± 46 0.21 212 ± 48 216 ± 45 0.34
LDL-cholesterol, mg/dL 138 ± 42 132 ± 45 140 ± 41 0.13 139 ± 42 138 ± 42 0.77
HDL-cholesterol, mg/dL 43 ± 14 49 ± 17 42 ± 12 <0.001 51 ± 15 38 ± 9 <0.001
Triglycerides, mg/dL 145(97-218) 112(70-165) 151(106-229) 0.02 108(76-136) 184(135-261) <0.001
Glucose, mg/dL 101(92-120) 96(89-107) 103(93-126) 0.002 95(88-102) 112(98-140) <0.001
hsCRP, mg/L 0.82(0.46-1.15) 0.59(0.40-0.89) 0.91(0.48-1.20) 0.043 0.59(0.25-0.93) 0.99(0.65-1.34) 0.005
Risk factors              
Hypertension, N (%) 213 (51) 35 (39) 178 (55) 0.13 47 (26) 166 (70) <0.001
Diabetes, N (%) 89 (22) 15 (4) 74 (18) 0.004 7 (4) 74 (31) <0.001
Hypercholesterolemia, N (%) 261 (62) 52 (58) 209 (64) 0.16 103 (62) 158 (75) 0.007
Smoking, N (%) 245 (59) 54 (60) 191 (59) 0.83 96 (54) 149 (63) 0.051
CAD, N (%) 215 (51) 40 (44) 175 (53) 0.13 69 (39) 146 (61) <0.001
Diseased coronary arteries 1.7 ± 0.9 1.8 ± 1.0 1.8 ± 0.9 0.98* 1.6 ± 0.9 1.8 ± 0.9 0.10*
BMI: Indicates Body-Mass Index; CAD: Coronary Artery Disease; hsCRP: High-Sensitivity C-Reactive Protein, LDL: Low Density Lipoprotein, HDL: High Density Lipoprotein. Categorical variables are presented as absolute (relative) frequencies; continuous variables, as mean ± SD or median (interquartile range).
P-values for between groups comparisons are derived from student’s t-test for unpaired measures (for continuous variables) or from chi-square tests (for categorical variables).
*P-value for comparison within the CAD patients.
Table 1: Baseline characteristics of the whole study population and according to presence of overweight/obesity and metabolic syndrome (MetS).