|   | 
        All    patients | 
        Normal weight | 
        Overweight/ obese | 
        P-value | 
        No MetS | 
        MetS | 
         P-value | 
       
      
        | N (%) | 
        418 | 
        90 (22) | 
        328 (78) | 
          | 
        179 (43) | 
        239 (57) | 
          | 
       
      
        | Age, years | 
        55.2     ±  11.3 | 
        55.8     ±  13.0 | 
        55.1     ±  10.8 | 
        0.59 | 
        53.7     ±  10.3 | 
        56.3     ±  10.3 | 
        0.021 | 
       
      
        | Gender,    males/females | 
        239/179 | 
        49/41 | 
        190/138 | 
        0.55 | 
        91/88 | 
        148/91 | 
        0.023 | 
       
      
        | Weight, kg | 
        85     ±  19 | 
        66     ±  9 | 
        90     ±  18 | 
        <0.001 | 
        77     ±  17 | 
        91     ±  19 | 
        <0.001 | 
       
      
        | Height, cm | 
        169     ±  10 | 
        168     ±  10 | 
        169     ±  11 | 
        0.64 | 
        168     ±  10 | 
        169     ±  11 | 
        0.2 | 
       
      
        | BMI, kg/m2 | 
        29.7     ±  6.2 | 
        22.7     ±  2.1 | 
        31.6     ±  5.5 | 
        <0.001 | 
        27.1     ±  5.8 | 
        31.7     ±  5.8 | 
        <0.001 | 
       
      
        | Mean blood pressure,    mmHg | 
        109     ±  15 | 
        105     ±  15 | 
        110     ±  15 | 
        0.018 | 
        105     ±  15 | 
        111     ±  15 | 
        <0.001 | 
       
      
        | Total cholesterol, mg/dL | 
        214     ±  46 | 
        209     ±  48 | 
        216     ±  46 | 
        0.21 | 
        212     ±  48 | 
        216     ±  45 | 
        0.34 | 
       
      
        | LDL-cholesterol, mg/dL | 
        138     ±  42 | 
        132     ±  45 | 
        140     ±  41 | 
        0.13 | 
        139     ±  42 | 
        138     ±  42 | 
        0.77 | 
       
      
        | HDL-cholesterol, mg/dL | 
        43     ±  14 | 
        49     ±  17 | 
        42     ±  12 | 
        <0.001 | 
        51     ±  15 | 
        38     ±  9 | 
        <0.001 | 
       
      
        | Triglycerides, mg/dL | 
        145(97-218) | 
        112(70-165) | 
        151(106-229) | 
        0.02 | 
        108(76-136) | 
        184(135-261) | 
        <0.001 | 
       
      
        | Glucose, mg/dL | 
        101(92-120) | 
        96(89-107) | 
        103(93-126) | 
        0.002 | 
        95(88-102) | 
        112(98-140) | 
        <0.001 | 
       
      
        | hsCRP, mg/L | 
        0.82(0.46-1.15) | 
        0.59(0.40-0.89) | 
        0.91(0.48-1.20) | 
        0.043 | 
        0.59(0.25-0.93) | 
        0.99(0.65-1.34) | 
        0.005 | 
       
      
        | Risk    factors | 
          | 
          | 
          | 
          | 
          | 
          | 
          | 
       
      
        | Hypertension, N (%) | 
        213 (51) | 
        35 (39) | 
        178 (55) | 
        0.13 | 
        47 (26) | 
        166 (70) | 
        <0.001 | 
       
      
        |  Diabetes, N (%)  | 
        89 (22) | 
        15 (4) | 
        74 (18) | 
        0.004 | 
        7 (4) | 
        74 (31) | 
        <0.001 | 
       
      
        | Hypercholesterolemia, N (%)  | 
        261 (62) | 
        52 (58) | 
        209 (64) | 
        0.16 | 
        103 (62) | 
        158 (75) | 
        0.007 | 
       
      
        | Smoking, N (%)  | 
        245 (59) | 
        54 (60) | 
        191 (59) | 
        0.83 | 
        96 (54) | 
        149 (63) | 
        0.051 | 
       
      
        | CAD, N (%)  | 
        215 (51) | 
        40 (44) | 
        175 (53) | 
        0.13 | 
        69 (39) | 
        146 (61) | 
        <0.001 | 
       
      
        | Diseased    coronary arteries | 
        1.7 ± 0.9 | 
        1.8 ± 1.0 | 
        1.8 ± 0.9 | 
        0.98* | 
        1.6 ± 0.9 | 
        1.8 ± 0.9 | 
        0.10* | 
       
     
      BMI: Indicates Body-Mass Index; CAD: Coronary Artery Disease; hsCRP: High-Sensitivity C-Reactive Protein, LDL: Low Density Lipoprotein, HDL: High Density Lipoprotein.
    Categorical variables are presented as absolute (relative) frequencies; continuous variables, as mean ± SD or median (interquartile range). 
    P-values for between groups comparisons are derived from student’s t-test for unpaired measures (for continuous variables) or from chi-square tests (for categorical
    variables). 
    *P-value for comparison within the CAD patients. |