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Figure 5: Effect of KSE on ROS generation in Aβ (1-42)-induced neurons. Hippocampus neurons were pretreated for 1 h with various concentrations (7.5 or 50 μL KSE). After 1 h, the cells were treated with 10 μM Aβ (1–42) for 48 h. The increase of DCF-DA fluorescence was measured by fluorescence microplate reader (λex485 nm/λem535 nm). The ROS productions of control and KSE are indicated by shaded columns. Values are the mean ± SD of three measurements. **p<0.01, *p<0.05 compared with the controls. |