eGFR=60mL/min/1.73m2 eGFR<60mL/min/1.73m2 p value *
  Albuminuria <30mg/g Albuminuria ≥30mg/g
N 112,015 2,613 3,686  
Age (years) 53.5 ± 8.6 56.7 ± 9.5 60.8 ± 9.2 <0.00001
Men (%) 52.1 71.3 33.2 <0.00001
Hypertension (%) 43.4 74.7 63.3 <0.00001
Treated hypertension (%) 16.4 33.3 38.9 <0.00001
Diabetes (%) 5.0 20.8 8.5 <0.00001
Lipid-lowering drug (%) 12.5 22.4 27.4 <0.00001
BMI (kg/m2) 25.7 ± 4.4 28.1 ± 5.6 26.8+-4.8 <0.00001
Obesity† (%) 14.6 32.1 21.3 <0.00001
SBP (mmHg) 134 ± 17 148 ± 21 139 ±19 <0.00001
DBP (mmHg) 80 ± 10 87 ± 12 81 ±10 <0.00001
Waist circumference (cm) 88.2 ± 12.7 96.8 ± 14.4 89.8 ±13.6 <0.00001
Total cholesterol (mmol/L)‡ 5.66(5.04-6.31) 5.66(4.94-6.41) 5.72(5.04-6.41) 0.0007
LDL-cholesterol (mmol/L) 3.65 ± 0.86 3.58 ± 0.99 3.66 ± 0.90 <0.00001
Triglycerides 1.05(0.79-1.46) 1.35(0.96-1.95) 1.14 (0.84-1.57) <0.00001
HDL-cholesterol (mmol/L) 1.49 ±0.36 1.39 ±0. 41 1.48 ±0.38 <0.00001
Fasting plasma glucose (mmol/L)‡ 5.11(4.77-5.49) 5.44(5.00-6.22) 5.11(4.77-5.55) <0.00001
Serum uric acid(mg/L) 45.27 ± 12.83 52.15 ± 14.52 50.42 ±14.96 <0.00001
Metabolic syndrome (NCEP ATP III)(%) 16.1 41.4 29.9 <0.00001
Diabetes risk score  (DESIR score)§ 2.4 ± 1.2 3.1 ± 1.2 2.8 ± 1.2 <0.00001
Fatty Liver Index|| 35.6 ± 28.1 56.1 ±30.7 44.9 ±29.2 <0.00001
Low physical activity (%) 76.6 83.3 80.0 0.00004
Values are expressed as mean ± standard deviation or percentages.
*Comparison between the three groups were made by covariance analysis for continuous data or logistic regression for discrete data with adjustments on age and gender.
†Obesity: BMI ≥ 30kg/m2
‡Median (25% - 75% quartiles).
§Diabetic subjects excluded [6]
׀׀Subjects with excessive alcohol consumption excluded [22]
eGFR: estimated Glomerular Filtration Rate; BMI: Body Mass Index; SBP: Systolic Blood Pressure; DBP: Diastolic Blood Pressure; LDL: Low-Density Lipoprotein; HDL: High-Density Lipoprotein, DESIR : Data From The Epidemiological Study On The Insulin Resistance Syndrome
Table 1: Characteristics of the population