| eGFR=60mL/min/1.73m2 |
eGFR<60mL/min/1.73m2 |
p value * |
| |
Albuminuria <30mg/g |
Albuminuria ≥30mg/g |
| N |
112,015 |
2,613 |
3,686 |
|
| Age (years) |
53.5 ± 8.6 |
56.7 ± 9.5 |
60.8 ± 9.2 |
<0.00001 |
| Men (%) |
52.1 |
71.3 |
33.2 |
<0.00001 |
| Hypertension (%) |
43.4 |
74.7 |
63.3 |
<0.00001 |
| Treated hypertension (%) |
16.4 |
33.3 |
38.9 |
<0.00001 |
| Diabetes (%) |
5.0 |
20.8 |
8.5 |
<0.00001 |
| Lipid-lowering drug (%) |
12.5 |
22.4 |
27.4 |
<0.00001 |
| BMI (kg/m2) |
25.7 ± 4.4 |
28.1 ± 5.6 |
26.8+-4.8 |
<0.00001 |
| Obesity† (%) |
14.6 |
32.1 |
21.3 |
<0.00001 |
| SBP (mmHg) |
134 ± 17 |
148 ± 21 |
139 ±19 |
<0.00001 |
| DBP (mmHg) |
80 ± 10 |
87 ± 12 |
81 ±10 |
<0.00001 |
| Waist circumference (cm) |
88.2 ± 12.7 |
96.8 ± 14.4 |
89.8 ±13.6 |
<0.00001 |
| Total cholesterol (mmol/L)‡ |
5.66(5.04-6.31) |
5.66(4.94-6.41) |
5.72(5.04-6.41) |
0.0007 |
| LDL-cholesterol (mmol/L) |
3.65 ± 0.86 |
3.58 ± 0.99 |
3.66 ± 0.90 |
<0.00001 |
| Triglycerides |
1.05(0.79-1.46) |
1.35(0.96-1.95) |
1.14 (0.84-1.57) |
<0.00001 |
| HDL-cholesterol (mmol/L) |
1.49 ±0.36 |
1.39 ±0. 41 |
1.48 ±0.38 |
<0.00001 |
| Fasting plasma glucose (mmol/L)‡ |
5.11(4.77-5.49) |
5.44(5.00-6.22) |
5.11(4.77-5.55) |
<0.00001 |
| Serum uric acid(mg/L) |
45.27 ± 12.83 |
52.15 ± 14.52 |
50.42 ±14.96 |
<0.00001 |
| Metabolic syndrome (NCEP ATP III)(%) |
16.1 |
41.4 |
29.9 |
<0.00001 |
| Diabetes risk score (DESIR score)§ |
2.4 ± 1.2 |
3.1 ± 1.2 |
2.8 ± 1.2 |
<0.00001 |
| Fatty Liver Index|| |
35.6 ± 28.1 |
56.1 ±30.7 |
44.9 ±29.2 |
<0.00001 |
| Low physical
activity (%) |
76.6 |
83.3 |
80.0 |
0.00004 |
Values are expressed as mean ± standard deviation or percentages.
*Comparison between the three groups were made by covariance analysis for continuous data or logistic regression for discrete data with adjustments on age and gender.
†Obesity: BMI ≥ 30kg/m2
‡Median (25% - 75% quartiles).
§Diabetic subjects excluded [6]
׀׀Subjects with excessive alcohol consumption excluded [22]
eGFR: estimated Glomerular Filtration Rate; BMI: Body Mass Index; SBP: Systolic Blood Pressure; DBP: Diastolic Blood Pressure; LDL: Low-Density Lipoprotein; HDL:
High-Density Lipoprotein, DESIR : Data From The Epidemiological Study On The Insulin Resistance Syndrome |
