Diabetes mellitus & AMI (ICD)
Type 1 diabetes mellitus: DE100, DE101, DE109, 24900, 24909, 24907, 24906
Type 2 diabetes mellitus: DE110, DE111, DE119, 25006, 25007, 25009
AMI: DI21, DI22, DI23, 41009, 41099
Comorbidities (ICD)
Stroke (DI63, DI64, 433, 434,436), atrial fibrillation (DI48, 42793, 42794), nephropathy (DE102, DE112, 24902, 25002), neuropathy (DE104, DE114, 24903, 25003), retinopathy (DE103, DE113, 24901, 25001), peripheral artery disease (DE105, DE115, 24904, 24905, 25004, 25005), heart failure (DI50, DI110, DI130, DI132, 42709-42711, 42719, 42899), alcohol (DF10, 303)
Antidiabetic drugs, antihypertensive drugs, statins, antiarrhythmic drugs (ATC)
Insulin (A10A), biguanides (A10BA), β-cell stimulating (A10BB), glitazones (A10BG), DPP-4 inhibitors (A10BH, A10BH01, A10BD07, A10BH02, A10BD08, A10BH03, A10BD10, A10BH05, A10BD11), liraglutide (A10BX07), exenatide (A10BX04), lixisenatide (A10BX10)
Antihypertensive drugs (C09, C07A, C08, C02AB, C02AC, C02CA, C02DB, C03C, C03AA, C03D)
Statins (C10AA)
Antiarrhythmic drugs (C01BD, C01AA, C01BC, C08DA, C01B)
Anticoagulants & thrombocyte inhibitors (ATC)
B01A, B01AA, B01AB, B01AX, B01AE, B01AF, B01AC, M01A, M01AH05, M01AH01, M01AH04, M01AB08, M01AB01, M01AB05, M01AA01, M01AE01, M01AE17, M01AC06, M01AC02, M01AE02, MAC01, M01AX01, M01AE14, M01AE11, M01AC02, M01AB15, M01AE52, M01AC05, N02BA)
Others (ATC)
Opioids (N02AB02, N02AB03, N02AA01, R05DA04, N02AA05, N02AX02, N02AE01, N07BC01), glucocorticoids (H02AB), bisphosphonates (M05BA), antipsychotics (N05A), antiepileptics (N03A), antidepressants (N06A), benzodiazepines N05BA, (N05CD)
Table 1: Evaluated exposure variables used in the adjusted, covariate analysis ICD codes are shown as both ICD10 and ICD8