| |
Variables |
Patients
(n=20) |
Healthy volunteers
(n=16) |
Significance |
| Basic data |
Age (years) |
58.3 (±12.0) |
62.6 (±10.5) |
NS |
| Sex (male/female) |
10/10 |
7/9 |
NS |
| Body Mass Index kg/m2 |
28.0 (±3.62) |
25.8 (±3.38) |
NS |
| Diabets duration (years) |
15.8 (±10.0) |
- |
- |
| HbA1c (%) |
8.0 (±1.0) |
- |
- |
| Hypertension% |
81 |
19 |
P=0.001 |
| Beta-blocker (%) |
27 |
0 |
P=0.04 |
| Sensorimotor
neuropathy |
First sensation Von Frey (g) |
*3.0 (0.8-12.5) |
*1.0 (0.4-1.4) |
P=0.03 |
| Sensory score (VAS) to
26 grinprick |
|
2.6±1.3 |
P=0.10 |
| Muscle pressure (KPa) |
1.9(±0.8)
358±171 |
283±110 |
P=0.12 |
| Autonomous
neuropathy |
Mean heart rate variability |
7.1±5.6 |
13.3±8.1 |
P=0.02 |
| Mean SD of heart rate |
3.3±2.0 |
5.6±2.8 |
P=0.01 |
| LF norm |
*44.3 (21-76) |
71.2 (57-87) |
P=0.04 |
| HF norm |
*55.7 (24-79) |
28.8(13-43) |
P=0.04 |
| LF/HF |
*0.8(0.27-3.3) |
2.47(1.3-6.8) |
P=0.04 |
| Conditioning
Pain modulation |
Absolute increase after CPM (kPa |
44±69 |
102±73 |
P=0.02 |
| Relative increase after CPM (%) |
14±15 |
37±29 |
P=0.005 |
