| |
Normotensive (n=657) |
GH (n=30) |
PE (n=46) |
P |
| Maternal characteristics |
| Maternal Age (years) |
32.9 (32.5-33.3) |
31.9 (29.5-34.2) |
31.44 (29.58-33.29) |
0.24 |
| Nulliparous n (%) |
204 (31.3) [652] |
13 (43.3) |
20 (43.5) |
0.10 |
| Metformin Treatment n (%) |
330 (50.2) |
20 (43.5) |
13 (43.3) |
0.53 |
| Caucasian n (%) |
319 (48.6) |
20 (66.7) |
18 (39.1) |
0.03 |
| Indian n (%) |
89 (13.5) |
3 (10.0) |
4 (8.7) |
| Polynesian n (%) |
134 (20.4) |
6 (20.0) |
19 (41.3) |
| Asian n (%) |
86 (13.1) |
1 (3.3) |
4 (8.7) |
| Other n (%) |
29 (4.4) |
0 |
1 (2.2) |
| Tertiary education n (%) |
292 (44.9) |
14 (46.7) |
17 (37.0) |
0.56 |
| Smoking in pregnancy n (%) |
106 (16.1) |
6 (20.0) |
9 (19.6) |
0.73 |
| Gestational age at enrolment (weeks) |
30.1 (29.8-30.3) |
30.5 (29.5-31.5) |
30.40 (29.62-31.18) |
0.93 |
| BMI at enrolment (kg/m2) |
34.60 (34.02-35.18) [656] |
36.83 (33.89-39.77) |
36.24 (34.02-38.46) |
0.14 |
| Maternal weight change from early pregnancy to enrolment |
6.50 (6.05-6.95) [533] |
9.45 (6.53-12.37) [29] |
9.44 (6.53-12.37) [29] |
0.15 |
| Systolic BP (mmHg) |
112.0 (111.0-113.0) [641] |
122.3 (117.9-126.8) |
124.9 (121.0-128.7) |
<0.001 |
| Diastolic BP (mmHg) |
67.6 (66.9-68.3) |
73.9 (70.3-77.4) |
77.0 (74.4-79.7) |
<0.001 |
| Fasting glucose (mmol/L) |
5.20 (5.12-5.28) [558] |
5.40 (4.85-5.96) [25] |
5.76 (1.61) [35] |
0.20 |
| HbA1c (%) |
5.73 (5.67-5.78) [598] |
5.86 (5.54-6.18) [27] |
6.14 (0.94) [39] |
0.01 |
| Fasting triglycerides (mmol/L) |
2.55 (2.47-2.62) [550] |
2.92 (2.26-3.58) [21] |
2.93 (2.57-3.29) [37] |
0.05 |
| Fasting cholesterol (mmol/L) |
6.07 (5.91-6.24) [342] |
5.80 (4.94-6.66) [16] |
5.82 (5.22-6.42) [22] |
0.34 |
| Fasting HDL-cholesterol (mmol/L) |
1.72 (1.67-1.76) [350] |
1.66 (1.49-1.83) [16] |
1.53 (1.38-1.68) [22] |
0.18 |
| Fasting LDL-cholesterol (mmol/L) |
3.21 (3.06-3.36) [342] |
2.77 (1.93-3.61) [14] |
2.87 (2.38-3.36) [22] |
0.16 |
| Infant characteristics |
| Gestational age at delivery (days) |
269.3 (268.6-270.0) |
270.0 (267.0-273.1) |
261.6 (258.4-264.8) |
<0.001 |
| Female gender n (%) |
322 (49.0) |
13 (43.3) |
20 (43.5) |
0.65 |
| Birth weight centile (%) |
54.10 (51.76-56.44) |
49.25 (39.15-59.35) |
52.44 (42.14-62.74) |
0.66 |
| <10th centile n (%) |
68 (10.4) |
2 (6.7) |
8 (17.4) |
0.25 |
| APGAR 1 min ** |
9 |
9 |
9 |
0.28 |
| APGAR 5 min ** |
9 |
10 |
10 |
0.23 |
| Cord glucose (mmol/L) |
4.73 (4.59-4.88) [417] |
4.33 (3.83-4.83) [19] |
4.23 (3.69-4.77) [15] |
0.24 |
| Cord triglycerides (mmol/L) |
0.41 (0.39-0.43) [419] |
0.45 (0.35-0.56) [19] |
0.52 (0.36-0.68) [15] |
0.16 |
