Figure 3: Thermal hyperalgesia (A) and mechanical allodynia (B) of non-diabetic rats (●, n=4) and diabetic rats treated with either saline (■, n=6) or Cris-104 (◆, n=6) at dose of 35 mg. kg-1. Treatment was initiated 4 weeks after STZ injection to induce diabetes. Data are mean ± SEM. * P<0.05 compared to control (BL) # P<0.05 compared to diabetic+saline