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Figure 5: Acylcarnitine contents in the gastrocnemius muscle at different time points after HFD feeding. Acylcarnitine contents in the gastrocnemius muscle samples from 5 months and 7 months after HFD fed mice were measured using electrospray ionization tandem mass spectrometry. (A) acylcarnitine profile, (B) 3- hydroxybutyryl-acylcarnitine (C4-OH), (C) hydroxydodecanoylacylcarnitine (C12-OH). #p<0.01, ## p<0.05 between different time points within the same strain mice, *p<0.05 WT vs. Cpt1b+/- within the same time point, n=5 per group. |